Nathaniel Hackett and the Denver Broncos (2-3) will battle Brandon Staley and the Los Angeles Chargers (3-2) in a primetime affair on Monday Night Football. Both squads want this win badly, so we can expect a high-energy contest to close out the Week 6 . The Broncos are 12-4 against the spread in their last 16 games after scoring Tyler Webb Jersey fewer than 15 points in their previous game. Meanwhile, the Chargers are 8-3 against the spread in their last 11 games versus the AFC West.Kickoff is at 8:15 p.m. ET in Los Angeles. Caesars Sportsbook lists Los Angeles as the 4.5-point home favorite, while the over/under, or total number of points Vegas thinks will be scored, is 45.5 in the latest Broncos vs. Chargers odds. Before locking in any Chargers vs. Broncos picks, .The model, which simulates every game 10,000 times, is up almost $7,000 for $100 players on top-rated since its inception. The model entered Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated that dates back to the 2017 season.The model also ranked Mike Shannon Jersey in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.Now, the model has set its sights on and just locked in its picks and MNF predictions. . Here are the and betting lines for Chargers vs. Broncos: Broncos vs. Chargers spread: Chargers -4.5Broncos vs. Chargers over/under: 45.5 pointsBroncos vs. Chargers money line: Chargers -220, Broncos +180DEN: Broncos are 1-4 against the spread this seasonLAC: Chargers are 4-1 against the spread this seasonBroncos vs. Chargers picks: Featured Game | Los Angeles Chargers vs. Denver Broncos Moneyline Spread Total LAC DEN Los Angeles is in the bottom 10 of the NFL in rushing yards this season and is averaging only 3.6 yards per carry. Los Angeles is also below average in both third down conversion rate (39.1%) and red zone efficiency (52.1%), and Denver enters Week 6 with one of the NFL's best defensive profiles. The Broncos allowed only 12 points in an overtime game last week, generating six sacks and stifling the Colts' offense. Denver leads the NFL Roger Maris Jersey in pa sing defense, yielding fewer than 180 yards per game, and is also atop the league in red zone efficiency allowed at 27.3%.Denver is in the top five in points allowed (16.0 per game and 1.30 per drive) and yards allowed (289.0 per game and 25.5 per drive), with the Broncos Jose Martinez Jersey pa s rush putting pre sure on opponents. Denver has a 36% pre sure rate and a 9% sack rate, keyed in large part by former top-five pick Bradley Chubb. .Los Angeles has an extremely talented secondary. Asante Samuel Jr. is an athletic and physical cornerback who makes plays on the ball. Samuel is third on the team in total tackles (21) and tied for first in pa s deflections (four). Bryce Callahan is another stout cornerback. He may be undersized (5-foot-9), but he's very instinctive and has a nose for the ball. The Rice product has logged 16 total tackles with four pa s deflections and a team-best two interceptions. J.C. Jackson rounds out this starting cornerback group. Jackson is exceptional in man coverage with ball-hawking skills. The Maryland product can quickly change directions and break on the ball in a hurry. He's recorded 10 stops and one pa s deflection Brett Cecil Jersey through three games. .SportsLine's model is leaning Over on the point total. In fact, it's calling for 47 combined points. It also says one of the spread has all the value. .So who wins Chargers vs. Broncos on Monday Night Football? And which side of the spread has all the value? , and find out.