The will play their -high fourth international game this Sunday, playing at London's Wembley Stadium for the fourth year in a row. The Jags are 1-2 in these games so far, having lost to the 49ers and in 2013 and 2014 before defeating the last season. This time around, the Jaguars will play a division game in London for the first time, taking on and the . Both teams need a win in the worst way. Jacksonville enters the contest at 0-3 while the Colts come in with a 1-2 record. The Jakob Johnson Jersey AFC South once again looks like the worst division in football, and it's wide open now with the division-leading (2-1) losing for the entire season. Dropping to 0-4 would seem to be a death knell for Jacksonville's season, while falling to 1-3 with an in-division lo s would put the Colts behind the eight-ball as well. Indianapolis has injury i sues all over -- No. 2 receiver is out, as are corners and -- and has struggled on both sides of the ball this year, but the Dont'a Hightower Jersey Jaguars have looked like they should be in the conversation for the NFL's worst team through three weeks. Can either of them get back on track?How to Watch What: Indianapolis Colts vs. Jacksonville Jaguars When: Sunday, Oct. 2, 9:30 a.m. ET Where: Wembley Stadium, London, England TV: CBS Streaming: Sunday Ticket: Online: (available to watch online after midnight) Odds: The Colts are currently a -3 favorite .Injury report Colts Donte Moncrief, WR - Out Darius Butler, New England Patriots Jackets CB - Out Patrick Robinson, CB - Out , G/T - Out , OLB - Questionable , CB - Questionable , S - Questionable , S - Questionable , WR - Questionable , C - Questionable Andrew Luck, QB - Questionable Jaguars , T - Out , TE - Out , CB - Questionable , S - Questionable , CB - Questionable , RB - Questionable , G - Questionable , DL - QuestionablePrisco's Pick The Jaguars are off to a rough start, but they still have Justin Herron Jersey six games in the division. This is the first. It's a home game for them, but it's also in London. But they aren't playing well. The Colts got their first victory, and they will get the second one Isaiah Wynn Jersey here as Andrew Luck plays big. Pick: Colts 31, Jaguars 23 NFL International Series The Colts-Jaguars game is the first of four international games the NFL will play this season. Here are the others: Sunday, Oct. 23: vs. at Twickenham Stadium, London, England - 9:30 a.m. ET Sunday, Oct. 30: vs. at Wembley Stadium, London, England - 9:30 a.m. ET Monday, Nov. 21: Houston Texans vs. at Estadio Azteca, Mexico City, Mexico - 8:30 p.m. ET